Stochastic gene expression: bacterial elites in chemotaxis
نویسندگان
چکیده
منابع مشابه
Stochastic gene expression: bacterial elites in chemotaxis
B acteria are highly plastic: a single genotype can display a range of phenotypes in response to different environmental conditions. Strikingly, there can be phenotypic variation even in the absence of environmental variation due to the stochastic nature of gene expression (Raj & van Oudenaarden, 2008). As a result, cells in bacterial populations typically differ from each other in their molecu...
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BACKGROUND Biological systems are inherently inhomogeneous and spatial effects play a significant role in processes such as pattern formation. At the cellular level proteins are often localised either through static attachment or via a dynamic equilibrium. As well as spatial heterogeneity many cellular processes exhibit stochastic fluctuations and so to make inferences about the location of mol...
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Chemotaxis is the directed motion of an organism toward environmental conditions it deems attractive and/or away from surroundings it finds repellent. Movement of flagellated bacteria such as Escherichia coli can be characterized as a sequence of smooth-swimming runs punctuated by intermittent tumbles. Tumbles last only a fraction of a second, which is sufficient to effectively randomize the di...
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Sensory systems rescale their response sensitivity upon adaptation according to simple strategies that recur in processes as diverse as single-cell signaling, neural network responses, and whole-organism perception. Here, we study response rescaling in Escherichia coli chemotaxis, where adaptation dynamically tunes the cells' motile response during searches for nutrients. Using in vivo fluoresc...
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Spatial organization of signalling is not an exclusive property of eukaryotic cells. Despite the fact that bacterial signalling pathways are generally simpler than those in eukaryotes, there are several well-documented examples of higher-order intracellular signalling structures in bacteria. One of the most prominent and best-characterized structures is formed by proteins that control bacterial...
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ژورنال
عنوان ژورنال: Molecular Systems Biology
سال: 2017
ISSN: 1744-4292,1744-4292
DOI: 10.15252/msb.20167458